Aromasin is an anti-androgen that acts on the estrogen receptors and prevents testosterone from binding with the estrogen receptor in tissues such as the uterus, ovaries and brain Aromasin. It is used to treat advanced stage breast cancers with a risk for hormone resistant prostate cancer. It is thought that the risk for prostate cancer may be reduced after the discontinuation of aromasin therapy. As there are many different anti-androgens the incidence of side effects can vary.
In the adjuvant therapy of premenopausal women, the most commonly observed side effects occurring in women who are taking aromasin were mild to moderate cold flashes (median of 2 nights), lightheadedness (median of more than half hour), hot flushes (median of more than 30 minutes), and sleepiness. In postmenopausal women, the most commonly observed side effects in women who are on aromasin therapy are hot flashes (often lasting several hours) and mild to severe vaginal dryness. The reported frequency of occurrence of side effects in postmenopausal women who were not on aromasin therapy was not significantly different from women in the postmenopausal group. Fluid retention is also noted in postmenopausal women taking aromasin, possibly due to the increased use of artificial sweeteners, diuretics and antacids. If patients must use diuretics, they should be advised to drink plenty of water, as antacids should not be taken with water.
Aromasin is available without a prescription in the US and Europe. Aromasin is marketed under several trade names and the active ingredient is tarsal tunnel oil. Tarsal tunnel oil is used in the preparation of dietary supplements for gastrointestinal functions and immune function. Aromasin can be purchased online or in health food stores without a prescription. There have been no reports of adverse reaction occurring in clinical trials with aromasin.
One of the few studies which examined the risk of allergic reaction to aromasin was conducted by the Center for Drug Evaluation (CDE). A nationwide blood survey was conducted to evaluate the risk of allergic reaction to 25 mg daily of the antacids aerosolized in the air and found no such incidence. The study also showed that there was no link between the use of aromasin in the treatment of asthma and the occurrence of anaphylactic shock. It was concluded that there was no link between the use of aromasin and the occurrence of anaphylactic shock.
Another common side effects associated with the use of aromasin and other antacids is the occurrence of stomach pain and cramps, which can lead to dehydration. Aromasin has been associated with a number of different types of gastro-intestinal disorders such as dyspepsia, nausea, and heartburn in some patients taking antacids for longer periods of time. Patients should be made aware of these side effects and the possibility that they may occur. It is also important for patients to be made aware of the fact that even though the risk of anaphylactic shock is minimal, it can occur in certain circumstances. Therefore, patients should be made aware of the importance of carefully reading the drug information which accompanies the products they intend to purchase and should ask their pharmacist questions which are important to them.
There is a potential for women to experience breast tenderness, chest pain, and lower back or abdominal pain, nausea, and vomiting. Abdominal swelling and nausea could also occur if the patient is pregnant. Abdominal pain with diarrhea or other constipation symptoms may be an indication that the woman is pregnant. A patient should not stop using aromasin without the consultation of their physician because the drug could be harmful to them.